Peer Reviewed Studies

Peer Review

A compilation of studies and articles on cleaning practices, efficacy and safety of certain chemistries.

The value of ready-to-use disinfectant wipes: Compliance, employee time, and costs

Assessment of RTU wipes and value they bring in compliance, costs, and labor vs cotton cloths and bucket method. To read full article visit:

http://www.ajicjournal.org/article/S0196-6553(13)01316-3/abstract

Efficacy of Accelerated Hydrogen Peroxide against important healthcare-associated pathogens

This article demonstrates the superior efficacy of Accelerated Hydrogen Peroxide disinfectants vs. other disinfectants on key healthcare associated pathogens.
This article can be accessed here:

http://www.ncbi.nlm.nih.gov/pubmed/23041817

Rutala AJIC June 2010 Role of the Environment

This article focuses on the role of surface contamination in the transmission of 3 emerging nosocomialpathogens: Norovirus, C. difficile, and Acinetobacter spp and literature supporting the use of EPA registered disinfectants for helping to control environmental transmission.

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AJIC – Omidbakhsh Sporicidal Activity of Surface Disinfectants Nov 2010

Available and fast-acting sporicides are generally corrosive and unsafe for both humans and the environment. The objective of the study was to compare a newly developed AHP-based Surface Sporicidal Agent that carries superior occupational health and compatibility profiles with to differing concentrations of Chlorine bleach.

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Survey of HBsAg-positive pregnant women and their infants regarding measures to prevent maternal-infantile transmission

The objective was to select a cleaning agent that had microbial killing ability that did not require an additional rinse step after application and had some C. difficile sporicidal activity within a short period of time. The evidence from this study shows that the Oxivir Tb formulation is a useful alternative to bleach for surface killing of C. difficile spores.

This study can be found here:

http://www.biomedcentral.com/1471-2334/10/26

Modeling microbial survival in buildup biofilm for complex medical devices

This study compares the disinfectant efficacy and microbial eradication of oxidizing-based disinfectant chemistries such as Accelerated Hydrogen Peroxide and cross-linking agents such as gluteraldehyde against both traditional and build-up biofilm.

This study can be found here:

http://www.biomedcentral.com/1471-2334/9/56

Identification by Quantitative Carrier Test of Surrogate Spore-Forming Bacteria To assess Sporicidal Chemicals for Use against Bacillus anthracis

Six strains of Bacillus anthracis (four virulent and two avirulent) were compared with four other types of spore-forming bacteria for their resistance to liquid chemical sporicides (sodium hypochlorite, accelerated hydrogen peroxide, chlorine dioxide and peracetic acid).

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An Accelerated Hydrogen Peroxide Based Microbicide for Manual Disinfection of Heat Sensitive Semi-Critical Medical Devices

The focus of this study was to assess the antimicrobial activity, stability and materials compatibility of a newly-developed AHP-based high level disinfectant in simulated reuse conditions.

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Is skin irritancy of the hand wash products solely related to their pH?

The study was designed to dispel the long-held notion that pH levels were directly related to skin irritancy through a scientific examination of the effects of pH on skin of five formulations.

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A new peroxide-based flexible endoscope-compatible high-level disinfectant

This article summarizes the efficacy, safety and materials compatibility of a 2% AHP-based high level disinfectant that is compatible with flexible endoscopes.

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Enhancing Patient Safety through management of Clostridium difficile at Toronto East General Hospital

A retrospective study of a Clostridium difficile outbreak and the interventions implemented that lead to a 50% decrease in the rates of C. difficile and corresponding decrease in MRSA rates.

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Broad-spectrum materials compatibility of a new generation of Accelerated Hydrogen Peroxide-based environmental surface disinfectant

This article summarizes the efficacy and safety of the EPA registered Intermediate Level disinfectant that is sold as Oxivir Tb in North America by Diversey.

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Activity of selected oxidizing microbicides against the spores of Clostridium difficile relevances to environmental control

This article summarizes the efficacy of several commonly used disinfectant chemistries and their relative effectiveness against the spores of Clostridium difficile.   AHP-based technology has been gaining acceptance as a means of formulating safer and environmentally benign microbicides with activity against major classes of nosocomial pathogens.

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Combined application of simulated reuse and quantitative carrier tests to assess high level disinfection experiments with an AHP based formulation

This article summarizes the efficacy and safety of a 7% AHP High Level Disinfectant and Chemosterilant.

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Product & Protocols for disinfection of hydrotherapy tubs

This study reviewed several products and protocols in order to develop guidelines for cleaning and disinfection of hydrotherapy tubs in long term care facilities.

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Evidence for Cleaning and Sanitizing Efficiency with AHP

This article summarizes the Health and Safety and Environmental Responsibility benefits of the Accelerated Hydrogen Peroxide

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A product based on accelerated and stabilized hydrogen peroxide. Evidence for broadspectrum germicidal activity.

This study summarizes the efficacy of a 0.5% Accelerated Hydrogen Peroxide surface cleaner-disinfectant.

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